A Rare Case of Brain Metastasis from dedifferentiated Acinic Cell Carcinoma of Parotid Gland and Review of the Literature

Acinic cell carcinoma (ACC) is a low or intermediate-grade malignant epithelial neoplasm of the salivary glands that generally shows an indolent behavior.Most cases arise in the major salivary glands, especially the parotid gland.ACC is usually known as a low-grade malignant tumor; however, poorly differentiated and high-grade transformed variants

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Loss of proteostatic control as a substrate for Atrial Fibrillation; a novel target for upstream therapy by Heat Shock Proteins

Chairside End Table Atrial Fibrillation (AF) is the most common, sustained clinical tachyarrhythmia associated with significant morbidity and mortality.AF is a persistent condition with progressive structural remodeling of the atrial cardiomyocytes due to the AF itself, resulting in cellular changes commonly observed in ageing and in other heart di

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